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XVIVO expands the US study with another leading transplant center

Barnes Jewish Hospital in St Louis, who pioneered lung transplantation, is the tenth transplant center to participate in the NOVEL trial. The Organ Procurement Organization (OPO) Mid-America Transplant Services has invested in an XPS in order to strengthen the collaboration between transplant centers and OPO's. This collaboration is the second of its kind in the USA.

Mid-American Transplant Services invested in an XPS™ and is collaborating with Barnes-Jewish Hospital in order to increase the utilization of lungs and enable transplants to more patients with severe lung disease. In 1988, Barnes-Jewish Hospital became one of the first hospitals in the United States with a program fully dedicated to lung transplantation surgery. The lung transplant program is one of the world's largest with more than 1,000 adult transplant surgeries performed.

The NOVEL trial was designed to safely increase the percentage of usable lungs from the donor pool. It is being performed at 10 centers in the United States. In the study, clinical outcomes after transplantation of lungs that have undergone warm perfusion after having been initially discarded are compared with a control group of lungs – non marginal – consisting of lungs that were initially assessed as non-transplantable. The results of the study indicate that lungs evaluated using STEEN Solution™ in an XPS™ do not differ in terms of safety and function from lungs transplanted directly. These results are consistent with those published from centers in Canada and Europe that have used STEEN Solution™ clinically and an equivalent technique.

“We are pleased that another well-known center has joined the NOVEL trial and that the connected OPO has invested in a XPS™. This collaboration is second of its kind in the US and will increase the utilization of lungs and give transplants to more patients with severe lung disease " says Dr. Magnus Nilsson CEO of XVIVO Perfusion.

January 29, 2014
XVIVO Perfusion AB (publ)

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