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Kidney Assist Transport™

Unlock the power of oxygen

XVIVO's Kidney Assist Transport is a portable device that allows hypothermic pulsatile perfusion of donor kidneys with oxygenated solution for up to 24 hours.

Benefits of Kidney Assist Transport™

Improved preservation

compared to SCS for DCD, DBD and ECD.

Plug & play

system for easy set-up, filling and dearing in unsterile setting.

Improved outcomes

with continuous HOPE compared to HMP in high-risk / DCD kidneys.

Improving transplantation outcomes

Hypothermic machine perfusion (HMP) is increasingly becoming standard of care when preserving and transporting kidneys for transplantation. Studies have demonstrated that standard HMP:

Significantly reduces the risk of delayed graft function, DGF, compared to static cold storage (SCS). This is true for both DBD and DCD kidneys [1].

Kidney Assist Transport leverages the clinical outcomes of standard HMP with the added benefits of continuous oxygenation, so called HOPE. The results from a multicenter, double-blinded, randomized controlled trial, comprising 106 donor pairs from DCD donors age ≥50, showed that recipients of HOPE treated kidneys at 1 year folllow-up experienced [2]:

11.7%

Improved renal function

73%

Fewer graft failures

44%

Lowered incidence of acute rejection

31%

Reduced incidence of severe post-transplant complications

REFERENCES

Improving transplantation outcomes

Tingle SJ, et al. Cochrane Database of Systematic Reviews, 2019
Jochmans I, et al. The Lancet, 2020

Kidney Assist Transport™ at a glance

READY-TO USE PERFUSION SET
Plug and play perfusion set that allows for easy set-up, filling and deairing in an unsterile setting.

HOLLOW FIBER MEMBRANE OXYGENATOR
Provides a high oxygen tension and concentration throughout the perfusion, optimizing oxygen transport efficiency.

PULSATILE PRO TECHNOLOGY
Centrifugal pump with pressure-controlled pulsatile flow has in preclinical studies shown to support microcirculation and improve functional outcome of kidney grafts.

UNIQUE PATCH & KIDNEY HOLDER DESIGN
Eliminates the need for cannulation and protects the kidney during transport.

Principles of operation

A continuously oxygenated machine perfusion solution is pumped through the kidney at hypothermic conditions. This allows for safe preservation of deceased donor kidneys up to 24 hours.