Liver Assist™
Unlock the power of flexibility
Benefits of Liver Assist™
Protocol of choice
enabled by flexible temperature range of 12-37°C.
Extended time
to ease transplantation logistics*.
Improved outcomes
for decreased donor transplant recipients.
Viability assessment
enabled by perfusion at near physiological conditions.
*up to 24 hours cold perfusion or 6 hours warm perfusion
Liver Assist has, since its introduction, emerged as the primary device utilized in major European trials. The system has been documented in over 85 peer-reviewed publications. Liver Assist provides clinicians a choice of perfusion protocols, whether it’s hypothermic (HOPE or DHOPE), normothermic, sub-normothermic, or a combination. These complementary protocols all serve different purposes from improving patient outcomes to increasing organ utilization.
Liver Assist™ at a glance
- Centrifugal pressure-controlled pumps provide an independent continuous flow on the portal vein side and a continuous pulsatile pattern on the hepatic artery side, similar to the physiological arterial perfusion (60 bpm)
- Flexible temperature-controlled perfusion 12-37°C
- Enables viability assessment during NMP
- Supports up to 24 hours hypothermic perfusion and 6 hours normothermic perfusion
- Hollow fiber membrane oxygenator provides a high oxygen tension and concentration throughout the perfusion, optimizing oxygen transport efficiency
Principles of operation
1. Liver reservoir: dedicated chamber giving access to the perfused liver while keeping it protected and humid
2. Pulsatile perfusion: mimicking physiological circumstances, the hepatic artery is perfused with a pulsatile flow
3. Oxygenation: oxygen/gas exchange via a separate hollow fiber oxygenator
4. Monitoring & sampling: Integrated sensors monitor real time flows, pressures and temperatures. Direct sampling options for analysis of perfusate
5. Continuous perfusion: mimicking physiological circumstances, the portal vein is perfused with a continuous flow
