STEEN Solution™
Unlock the power of confidence
Maintains stability of isolated lungs ex vivo
Facilitates assessment and allows for the stable perfusion of isolated lungs ex vivo.
Promotes rational use of a limited pool of donor lungs
Allows for initially rejected lungs to be used for transplantation, expanding the pool of available organs.
Normothermic functional assessment
STEEN Solution enables safe Ex Vivo Lung Perfusion (EVLP) and assessment of isolated lungs, increasing the number of donor lungs available for transplant.
Clinical evidence has verified that at least 6 hours of EVLP is safe with an acellular perfusate and that at least 2 hours is safe with a cellular perfusate. In the USA, the FDA has granted approval for up to 5 hours of EVLP with an acellular perfusate.
STEEN Solution™ is the most frequently used solution for normothermic EVLP
STEEN Solution was used in the first-ever clinical EVLP procedure in 2000 and continues to be the most frequently used solution for normothermic EVLP.
STEEN Solution™ at a glance
- The extracellular electrolyte composition, pH and human serum albumin simulate key properties of human blood plasma.
- Dextran 40 counteracts tissue oedema and protects the microvasculature against post-ischaemic reperfusion injury.
- Human serum albumin provides oncotic pressure preventing oedema.
Compatible technologies
STEEN Solution can be used together with the XPS, and manually with the accessories XVIVO Organ Chamber™ and XVIVO Lung Cannula.**
** In the US, STEEN Solution shall be used with the XPS. STEEN Solution is included in the XPS Disposable Lung Kit. Refer to local product labeling for approved indications and configurations.
