{"id":2941,"date":"2018-12-07T12:30:00","date_gmt":"2018-12-07T12:30:00","guid":{"rendered":"https:\/\/www.xvivogroup.com\/us\/mfn_news\/professor-stig-steens-heart-preservation-technology-required-for-successful-transplantation-from-pigs-to-baboons\/"},"modified":"2018-12-07T12:30:00","modified_gmt":"2018-12-07T12:30:00","slug":"professor-stig-steens-heart-preservation-technology-required-for-successful-transplantation-from-pigs-to-baboons","status":"publish","type":"mfn_news","link":"https:\/\/www.xvivogroup.com\/us\/pressreleases\/professor-stig-steens-heart-preservation-technology-required-for-successful-transplantation-from-pigs-to-baboons\/","title":{"rendered":"Professor Stig Steen\u2019s heart preservation technology required for successful transplantation from pigs to baboons"},"content":{"rendered":"<div class=\"mfn-preamble\"><strong>According to an article published earlier this week in the scientific journal Nature, use of Professor Stig Steen\u2019s heart preservation technology is required for successful xenotransplantation from pigs to baboons. This is an important step for XVIVO as well, as XVIVO\u2019s heart preservation products are based on this technology and XVIVO owns all commercial rights to the technology.<\/strong><\/div>\n<p><span>The well-reputed scientific journal Nature published earlier this week an article from Munich University Hospital which describes, the long-term survival of baboons that had received a heart transplant from genetically modified pigs. This is an important step forward on the way to being able to give humans porcine heart transplants. The article describes two requirements that have enabled the good results. One of these requirements being the introduction of non-ischemic (no shortage of oxygen) heart preservation in accordance with the method using the products developed by Professor Stig Steen, and the other requirement being inhibition of post-transplantation growth of the heart, which otherwise would become too big for the primate. <\/span><\/p>\n<p><span>These good results are in accordance with earlier experience that have led to XVIVO, as earlier communicated, is working intensively on submitting an application to the Swedish Medical Products Agency. The submission is planned for in approximately one month and is a prerequisite for a multicenter study on XVIVO\u2019s products for heart preservation. These products consist of a preservation solution which has the same composition as that clinically used in the heart transplant study ongoing at the University Hospitals of Lund, earlier pre-clinical studies and now pre-clinically used in Munich for heart preservation in xenotransplantation. The technology also includes a portable heart preservation machine incorporating a single-use component which has been constructed by XVIVO, in accordance with Professor Steen\u2019s technology.<\/span><\/p>\n<p><span>\u201cThere is currently sufficient data available to be able to suppose that non-ischemic heart preservation is a safe technique and, as the company earlier communicated, that it is time to initiate a multicenter study with aim of regulatory approval,\u201d says Magnus Nilsson, XVIVO Perfusion\u2019s CEO.<\/span><\/p>\n<p><span>December 7, 2018<br \/><\/span>Gothenburg<br \/>Magnus Nilsson, CEO<br \/>XVIVO Perfusion AB (publ)<\/p>\n<div class=\"mfn-footer\">\n<p><span>For further information please contact:<\/span><\/p>\n<p><span>Christoffer Rosenblad, CFO, +46 735 192159, christoffer.rosenblad@xvivoperfusion.com<br \/>Magnus Nilsson, CEO, +46 31 788 2150, magnus.nilsson@xvivoperfusion.com<\/span><br \/><span>For further information on XVIVO Perfusion\u2019s business, please refer to the company\u2019s website, www.xvivoperfusion.com<\/span><\/p>\n<p><span>The information was submitted for publication, through the agency of the contact person set out above, at 1:30 pm CET on December 7, 2018.<\/span><\/p>\n<p><span>This is a translation of the Swedish version of the press release. When in doubt, the Swedish wording prevails.<\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>According to an article published earlier this week in the scientific journal Nature, use of Professor Stig Steen\u2019s heart preservation&#8230;<\/p>\n","protected":false},"template":"","class_list":["post-2941","mfn_news","type-mfn_news","status-publish","hentry","mfn-news-tag-mfn","mfn-news-tag-mfn-type-ir","mfn-news-tag-mfn-lang-en","mfn-news-tag-mfn-ci","mfn-news-tag-mfn-ci-other"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Professor Stig Steen\u2019s heart preservation technology required for successful transplantation from pigs to baboons - XVIVO<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.xvivogroup.com\/us\/pressreleases\/professor-stig-steens-heart-preservation-technology-required-for-successful-transplantation-from-pigs-to-baboons\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Professor Stig Steen\u2019s heart preservation technology required for successful transplantation from pigs to baboons - 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